It has been an eventful year in the big pharma and biotech space, and a lot is happening in this space that biotech investors should take note of.

June E-mini S&Ps (ESM14 -0.47%) this morning are down -0.40% and European stocks are down -0.64% after the World Bank cut its global 2014 GDP forecast to 2.8% from a Jan estimate of 3.2%.