Biomarin is purchasing Prosensa for approximately $840 million.

The raised outlook reflects the continued strong performance of Vimizim and updated expectations. The market responded positively today.

The average large cap score is 58.41, below the four week moving average score of 65.67. The average large cap is trading -10.26% below its 52 week high, 4.07% above its 200 dma, has 3.42 days to cover held short and is expected to post EPS growth of 13.87% next year.

Our weekly best and worst reports show you stocks with the best potential returns over the coming 6 to 12 months. The best scoring large cap sector is industrial goods. The top scoring large cap industry is drug stores.

Our weekly best and worst large cap report show you the stocks with the best potential returns over the coming six to twelve months.

The highest scoring names in large cap from 1 year ago (1/29/2013) returned 334 bps more than the S&P 500. The best performers have been YHOO up 92%, BSX up 88%, and LNKD up 75%.